Navigating the Burden of Glioblastoma- Diagnosis to Treatment: Current Status and Future Perspectives

Glioblastoma (GBM) commonly presents with symptoms including headaches, seizures, nausea, vomiting, and cognitive decline. The specific symptoms experienced may differ based on the tumor's location and size inside the brain. The precise etiology of GBM remains uncertain, while certain risk factors like as radiation exposure, genetic susceptibility, and advanced age have been found. The results of functional imaging provide proof that a tumor has a widespread impact on the brain during its progression. To be more specific, a wide variety of neurological illnesses, such as GBM/HGG, have the ability to change the resting-state functional connectivity (rsFC), which is a measure that describes the functional organization in the brain. Glioblastoma multiforme (GBM) has a tendency to swiftly invade the neighboring brain tissue, posing challenges for full surgical extraction.