Xeroderma Pigmentosa: High Risk for Ocular Neoplasia

Elawamry, Amr I. and El-Moatassem Kotb, Ahmed M. and Hany, Sameh (2014) Xeroderma Pigmentosa: High Risk for Ocular Neoplasia. Open Journal of Ophthalmology, 04 (04). pp. 120-123. ISSN 2165-7408

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Abstract

Aim of Work: The aim of our work was early cytological and laboratory detection of any ocular surface malignant changes in xeroderma pigmentosa. Patients and Methods: Eighteen cases with xeroderma pigmentosa were included in this study. All cases were subjected to full ophthalmolog-ical examination, conjunctival biopsy from any abnormal lesion, polymerase chain reaction assay and impression cytology. Results: All cases were boys; the mean age was 11 years old. The main ocular presentation was dryness and abnormal epibulbar masses in different locations. Polymerase chain reaction represents precipitation of malignant cells which was confirmed by impression cytology. Conclusion: PCR and impression cytology are beneficial investigations for detection of any malignant changes in xeroderma pigmentosa.

Item Type: Article
Subjects: Middle East Library > Medical Science
Depositing User: Unnamed user with email support@middle-eastlibrary.com
Date Deposited: 04 Feb 2023 09:06
Last Modified: 25 May 2024 09:18
URI: http://editor.openaccessbook.com/id/eprint/197

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