Prevalence of beta-lactamases in Salmonella and Shigella species in different hospitals in Anyigba, Kogi State, Nigeria

Eze, E A and Ocean, H O and Eze, C N (2015) Prevalence of beta-lactamases in Salmonella and Shigella species in different hospitals in Anyigba, Kogi State, Nigeria. African Journal of Microbiology Research, 9 (3). pp. 180-184. ISSN 1996-0808

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Abstract

Beta-lactams are the most widely used antibiotics. Resistance to beta-lactam antibiotics is an increasing problem worldwide and beta-lactamase production is the most common mechanism of resistance to these drugs. Species of Salmonella and Shigella isolated from hospital patients in Anyigba, Kogi State, were analyzed for the presence of beta–lactamases using Nitrocefin, Iodometric, Acidimetric and Double Disc Synergy methods. Results showed that 9 (81.82%) of Shigella species and 22 (61.11%) of Salmonella species were beta-lactamase producers with 3 (27.27%) of Shigella species and 20 (55.56%) of Salmonella species producing extended spectrum beta-lactamases (ESBLs). Beta-lactamase production is an acknowledged threat to modern medicine especially antibiotic usage.

Item Type: Article
Subjects: Middle East Library > Biological Science
Depositing User: Unnamed user with email support@middle-eastlibrary.com
Date Deposited: 13 Apr 2023 07:20
Last Modified: 13 Sep 2024 07:49
URI: http://editor.openaccessbook.com/id/eprint/537

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